Reviewing the role of healthy volunteer studies in drug development | Journal of Translational Medicine | Full Text
Moving Beyond 3+3: The Future of Clinical Trial Design | American Society of Clinical Oncology Educational Book
Prediction of Drug Approval After Phase I Clinical Trials in Oncology: RESOLVED2 | JCO Clinical Cancer Informatics
Predefined dose-limiting toxic effects | Download Table
Designs of drug-combination phase I trials in oncology: a systematic review of the literature - Annals of Oncology
Illustration of the chronic dose-limiting toxicity (DLT) concept. (*)... | Download Scientific Diagram
On Biostatistics and Clinical Trials: Dose Limiting Toxicity (DLT) and Common Toxicity Criteria (CTC) / Common Terminology Criteria for Adverse Events (CTCAE)
On Biostatistics and Clinical Trials: July 2021
Determinants of the Recommended Phase 2 Dose of Molecular Targeted Agents
Definitions of dose limiting toxicity. | Download Table
University of Colorado Cancer Center - ppt download
Guidance for Industry Acute Myeloid Leukemia: Developing Drugs and Biological Products for Treatment
Phase I trials - memoinOncology
Application Type sNDA Application Number(s) 201023/S-20 Priority or Standard Priority Submit Date(s) November 21, 2016 Received
On Biostatistics and Clinical Trials: Dose Limiting Toxicity (DLT) and Common Toxicity Criteria (CTC) / Common Terminology Criteria for Adverse Events (CTCAE)
Phase I Trials of Chemotherapy and Targeted Agents - ppt video online download
ELIZABETH GARRETT-MAYER (SOME SLIDES BY PAT LORUSSO OF KARMANOS CANCER INSTITUTE WAYNE STATE UNIVERSITY) Phase I Trials of Chemotherapy and Targeted Agents. - ppt download
Early phase clinical trials to identify optimal dosing and safety - ScienceDirect
Practical Considerations - ppt download
On Biostatistics and Clinical Trials: Dose Limiting Toxicity (DLT) and Common Toxicity Criteria (CTC) / Common Terminology Criteria for Adverse Events (CTCAE)
Adaptive Design Methods in Clinical Trials - ppt download
First Dose to Man : general principles (Estimating Safe Dose)
Predictive Toxicology Approaches for Small Molecule Oncology Drugs
definition of dose-limiting toxicity. | Download Table
Towards new methods for the determination of dose limiting toxicities and the assessment of the recommended dose for further studies of molecularly targeted agents – Dose-Limiting Toxicity and Toxicity Assessment Recommendation Group
Guidance for Industry
